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This is noted as a side effect of the hormone ablation injection, lupron or zolodex and i'm not exactly sure why but in many cases when men receive this shot they also get a prescription for casodex that blocks the hormone from entering the cells of the prostate. when a man gets the shot his body is still producing testosterone and won't stop producing it for several days after getting the shot so during this time his psa can still go up. i assume he has prostate cancer and i went through the same treatment 10 years ago. my psa was 9.3 on 12-26-2001. i had the shot of zolodex on 1-18--2002 and my psa was down to 1.4 on 2-26-2002 which was about 5 weeks later but i was also taking th casodex to block the testosterone from entering the cells. once your testosterone productions stops the psa in your blood stream still takes some time to clear out and cancer cells produce 10 times more psa than normal prostate cells. after i had the brachytherapy (radioactive seeding) i had 7 weeks of external beam radiation on the prostate 3 weeks later to make sure all of the cancer cells were killed.
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